| First Ceremonial Pitch: |
Kim Shockley-Hampton to Progressive CEO Glenn Renwick, low and outside |
| Opening "play ball!" announcement: |
Anthony Fredericks of New Philadelphia, Ohio |
| Game time temperature: |
64 degrees |
| First batter: |
Nick Swisher, Chicago White Sox (CWS) |
| First pitch: |
3:05 p.m. by C. C. Sabathia, Cleveland Indians (CLE), to Nick Swisher, CWS, a swinging strike |
| First base runner: |
Orlando Cabrera, CWS, walked with 1 out in first inning |
| First walk: |
Orlando Cabrera, CWS, 1 out in first inning |
| First stolen base: |
Orlando Cabrera, CWS, 1 out, first inning |
| First hit AND first home run AND first two-run home run: |
Jim Thome, CWS, home run, first inning, 1 out, 1 on |
| First run scored: |
Orlando Cabrera, CWS, first inning on Thome HR |
| First RBI: |
Jim Thome, CWS, drove in Orlando Cabrera, first inning, on home run |
| First strikeout: |
By Sabathia, CLE, Paul Konerko, CWS, 1 out in first inning, bases empty |
| First CLE hit and first single (by either team): |
Single by Victor Martinez, leading off second inning |
| First CLE run: |
Victor Martinez, second inning, scored on fielder's choice by Asdrubal Cabrera |
| First CLE RBI: |
Asdrubal Cabrera, fielders choice, second inning, drove in Victor Martinez |
| First CLE home run and first three-run home run: |
Franklin Gutierrez, second inning, 2 men on base, 1 out |
| First double: |
A. J. Pierzynski, CWS, 1 out in second inning |
| First CLE double: |
Travis Hafner, driving in Jason Michaels, 2 out, second inning |
| First solo home run: |
Grady Sizemore, CLE, second inning |
| First triple: |
N/A |
| First relief pitcher: |
Nick Masset, CWS, 2 out, 1 on, second inning |
| First time a team batted around (sent all nine men to the plate in a single inning): |
CLE, second inning |
| First relief pitcher, CLE: |
Jensen Lewis, 2 men on, 1 out, sixth inning |
| First double play: |
By Cleveland, eighth inning, A. Cabrera to J. Peralta to R. Garko to end a CWS scoring threat |
| First losing pitcher: |
Octavio Dotel, CWS |
| First winning pitcher: |
Rafael Betancourt, CLE |
| First save: |
Joe Borowski, CLE |
| First player substitution due to injury: |
Kelly Shoppach replaced Victor Martinez, top of third, after Martinez strained a quadriceps muscle trying to steal second to end the second inning |
| First seventh-inning stretch: |
5:37 p.m. |
| Game completed: |
6:26 p.m. |
| Game attendance: |
41,872 (sellout) |
